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Información sobre vacunas
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Actualizado por última vez: January 29, 2007 |
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- Entendiendo la enfermedad
- Vacunas disponibles
- Historia de la vacuna
- Quienes deben y quienes no deben recibir esta vacuna
- Calendario de dosis
- Efectividad de la vacuna
- Efectos secundarios conocidos
- Asuntos relacionados
- Referencias clave y fuentes de información adicional
- Requerimientos estatales de vacunación
- Datos importantes que los padres deben saber
- Preguntas frecuentes
- Información de los CDC acerca de la vacuna
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Entendiendo la enfermedad
Haemophilus influenzae type b (Hib) is a bacterium that can infect the outer lining of the brain causing meningitis. Hib is transmitted from person to person through mucus droplets that are spread by coughing or sneezing. Invasive Hib disease occurs most often at three months to three years of age, peaking at six to seven months of age. The disease is uncommon after age five years.
Hib can cause a wide variety of serious infections, including pneumonia, severe throat swelling that makes breathing difficult (epiglottitis), and infections of blood, bones, joints, and the covering of the heart. Complications of Hib meningitis include blindness, deafness, mental retardation, learning disabilities, and death. About 5% of children (500 out of every 10,000) with Hib meningitis die despite antibiotic treatment.
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Vacunas disponibles
The Hib vaccine is available as:
- Hib (alone)
- Hib in combination with DTaP (Diphtheria-Tetanus-acellular Pertussis) vaccine
- Hib in combination with recombinant hepatitis B (HBV) vaccine
Product: ActHIB® (Hib)
Manufacturer: Aventis Pasteur
Year Licensed: 1993
Product: HibTITER® (Hib)
Manufacturer: Wyeth Lederle
Year Licensed: 1990
Product: PedvaxHIB® (Hib)
Manufacturer: Merck
Year Licensed: 1989
Product: Comvax® (HBV-Hib)
Manufacturer: Merck
Year Licensed: 1996
For information on the thimerosal content in these vaccines, see the Food and Drug Administration at www.fda.gov/cber/vaccine/thimerosal.htm#t3
or Johns Hopkins University's Institute for Vaccine Safety at
www.vaccinesafety.edu/thi-table.htm |
Historia de la vacuna
The first Hib vaccine was licensed in 1985. Scientists later reformulated the vaccine so that it would be effective in children under 18 months of age, and the FDA licensed this improved version in 1987. The currently used Hib vaccine protects infants as young as six weeks old. Prior to universal Hib immunization, Hib was the most common cause of bacterial meningitis in infants and preschool-age children, and caused approximately 20,000 cases of invasive disease annually. |
Quienes deben y quienes no deben recibir esta vacuna
Who should receive the vaccine?
- Due to the high risk of disease in children, all children younger than five years should receive the Hib vaccine, beginning at two months of age.
- Children over five years usually do not need Hib vaccine. Older children or adults with specific health conditions such as sickle cell disease, HIV/AIDS, removal of spleen, bone marrow transplant, or cancer treatment with immune-suppressant drugs need to be protected from Hib by the vaccine.
Unimmunized children are at increased risk of developing Hib when they are:
- Daycare attendees
- Household contacts of someone with Hib
- Those with a low socioeconomic status
- African-American
- Native American
- Immunocompromised because of sickle-cell disease, leukemia, human immunodeficiency virus (HIV) infection, or the absence of the spleen
Who should not receive the vaccine?
- Children younger than six weeks old
- People who have had a life-threatening allergic reaction (anaphylaxis) to a previous dose of Hib vaccine should not receive additional doses.
- People who are moderately or severely ill should consult with their physician before receiving any vaccine.
This vaccine is recommended by:
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Advisory Committee on Immunization Practices of the Centers for Disease Control and Prevention
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American Academy of Pediatrics
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American Academy of Family Physicians
The complete childhood immunization schedule can be found at:
www.cdc.gov/nip/recs/child-schedule.PDF
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Calendario de dosis
Children should get the Hib vaccine at 2, 4, 6*, and a booster at 12 to 15 months of age.
*Depending on which Hib vaccine is used, a child may not need the dose at six months of age. The doctor or nurse will know whether or not this dose is needed.
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Efectividad de la vacuna
Hib is one of only two vaccines that are more effective at providing immunity than natural infection is--the other is tetanus vaccine. Although the Hib vaccine prevents only one form of meningitis, it has nearly eliminated what was once the most common cause of bacterial meningitis in infants and children in the United States. Since Hib vaccines were introduced, the incidence of invasive Hib disease in infants and children in the U.S. has decreased by 99%.
Healthy recipients of Hib vaccine may be susceptible to Hib disease for one to two weeks until antibodies are developed.
Children at increased risk for Hib because of severe combined immunodeficiency syndrome or IgG2 deficiency, and some children with severe immune deficiency from HIV infection or who are receiving chemotherapy for malignant neoplasms (growths), may not develop protective antibodies from the vaccine and may, or may not, benefit from additional doses.
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Efectos secundarios conocidos
Approximately 25% of children who receive the Hib vaccine experience mild side effects such as pain, redness, or swelling at the site of the shot, while more serious reactions are infrequent. Studies have shown that children who receive the Hib vaccine in combination with or at the same time as the DTaP vaccine are no more likely to experience side effects than children who receive only the DTaP vaccine.
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Asuntos relacionados
Questions about the relationship between diabetes and the Hib vaccine have surfaced. Scientific evidence has not supported a relationship. The rate of diabetes in vaccinated children has been compared with the rate in unvaccinated children who were born before the vaccine was available.
No association between the vaccine and the development of diabetes was found.
Please see the following for further information:
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Referencias clave y fuentes de información adicional
- American Academy of Pediatrics, Committee on Infectious Diseases. (2003). H. influenzae infections. In LK Pickering (Ed.), Red Book: Report of the Committee on Infectious Diseases (26th ed., pp. 293-301). Elk Grove Village, IL: Author.
- Centers for Disease Control and Prevention (CDC). (1998). Haemophilus influenzae type B (Hib): What you need to know [Vaccine Information Statement (VIS)].
- CDC, National Immunization Program (NIP). (2000). Haemophilus influenzae type B (Hib). In Vaccine-preventable childhood diseases [Online fact sheet].
- CDC, NIP. (2004). Hib. In W Atkinson, C Wolfe, S Humiston, and R Nelson (Eds.), Epidemiology and prevention of vaccine-preventable diseases ("The Pink Book") ( 8th ed., pp. 101-116). Atlanta: Author.
- Combination vaccines for childhood immunization: Recommendations of the Advisory Committee on Immunization Practices (ACIP), the American Academy of Pediatrics (AAP), and the American Academy of Family Physicians (AAFP). (1999). Pediatrics, 103(5), 1064-1068.
- Heath PT, Booy R, Azzopardi HJ, Slack MP, Fogarty J, Moloney AC, Ramsay ME, and Moxon ER. (2001). Non-type b Haemophilus influenzae disease: Clinical and epidemiologic characteristics in the Haemophilus influenzae type b vaccine era. Pediatric Infectious Disease Journal, 20(3), 300-305.
- Humiston SG and Good C. (2000). Vaccinating your child: Questions and answers for the concerned parent. Atlanta: Peachtree Publishers.
- National Association of Pediatric Nurse Practitioners (NAPNAP). Hibdisease.com
- Offit PA and Bell LM. (1999). Vaccines: What every parent should know (Rev. ed.). New York: IDG Books.
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Vea también nuestra galería de imágenes de enfermedades.
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Requisitos de vacunación estatales Vea si su estado requiere esta vacuna.
Información provista por los Centros para el Control y Prevención de Enfermedades sobre vacunas específicas y las enfermedades que previenen. Se requiere que los proveedores de la salud den esta información a sus pacientes antes de administrarles una vacuna.
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